During enforcement activity for Operation Hawksbill, officers carried out searches at two separate addresses in Wilson Drive, Hawick.
Dealer quantities of cannabis were found within both properties and two men aged 35 and 32 were all arrested along with a 31-year-old woman.
Another home in Grieve Avenue, Jedburgh was also searched yesterday during Operation Hawksbill where more cannabis was recovered inside and a 48-year-old man was subsequently charged with supply.
The total value of the cannabis seized is around £1,500 and all of those arrested will appear in court at a later date.
Detective Sergeant Alan Young from the Lothians and Scottish Borders Proactive CID Unit said: “Operation Hawksbill was established to tackle all forms of drug crime within the Borders and target those responsible for their production and distribution throughout the region.
“We are delighted to have seized this cannabis before it could make its way to our communities.
“Members of the public who are aware of drug crime in their area can report this to us on 101 or via Crimestoppers on 0800 555 111. Whenever we receive a report of criminal activity it will be acted on accordingly to bring those responsible to justice.”